Acute Chest Syndrome in patients with Sickle Cell Anemia: Report of two cases in pediatrics

Abstract

Introduction: Acute Chest Syndrome in sickle cell disease is defined as a process characterized mainly by fever and chest pain, accompanied by new infiltrates in the chest x-ray. Clinical Case: Patients may present with a chest syndrome as described in the second case, or develop it during a hospital stay caused by another process, as described in the first case. It is the second most common complication and can affect any age group, with an incidence peak between 2 and 4 years of age. It is a condition that can be very severe with life-threatening risk, so suspicion, recognition, and evolutionary monitoring determine the prognosis in many of them. Two cases of patients with Chest Syndrome who presented different prodromes are presented, where the multidisciplinary approach played a crucial role in the satisfactory evolution of both.