Hyperplastic Foveolar Gastropathy with Helicobacter pylori Coinfection

Abstract

Ménétrier's disease is a rare premalignant hypertrophic gastropathy. It is characterized by a thickening of the gastric folds, secondary to a hyperplasia of the foveolar mucosal cells, frequently associated with loss of enteric proteins and hypoalbuminemia and upper gastrointestinal tract symptoms such as epigastric pain, malaise, nausea and vomiting. It has been associated with infections in most of the published cases, Cytomegalovirus (CMV) and Helicobacter pylori (Hp).We present the case of a teenager with a history of refractory epilepsy, who is admitted due to convulsive status and during hospitalization he presents with high digestive bleeding with hemodynamic compromise. Diagnosing Ménétrier's disease by endoscopic findings and biopsy. We review the literature